The usual dosage of chidamide is one capsule (5mg) once daily, yet the specific medication must strictly follow the doctor's advice, and the dosage shall not be adjusted on your own. This drug is a prescription medicine mainly indicated for the treatment of specific types of lymphoma. The administration regimen shall be formulated based on the patient's condition, physical status and test results, and regular rechecks are required to monitor the therapeutic effect and safety.
Detailed Administration Instructions
1. Dosage and Course of Treatment
The standard recommended dosage of chidamide is 5mg (one capsule) twice a week (e.g., one capsule on Monday and Thursday respectively), or once daily with dosage adjustment based on the patient's condition. If the doctor prescribes "one capsule a day", the prescription must be strictly followed, and the dosage shall not be arbitrarily increased, decreased or the medication discontinued due to changes in symptoms.
2. Administration Time
It is recommended to take the medicine at the same fixed time every day (e.g., after breakfast) to reduce the risk of missed doses. If it is necessary to adjust the administration time, consult a doctor in advance. Some patients may choose to take the medicine with meals due to gastrointestinal reactions, which must be confirmed by a doctor.
3. Management of Missed Doses
If a dose is missed and less than 12 hours have passed, take the missed dose as soon as possible. If more than 12 hours have passed or the next scheduled dose is approaching, skip the missed dose. Do not take a double dose at one time.
4. Adverse Reactions and Management
Common adverse reactions include fatigue, diarrhea, thrombocytopenia, etc., which can usually be alleviated by dosage adjustment or symptomatic treatment. In case of severe infection, persistent fever or bleeding tendency (e.g., gingival bleeding, subcutaneous ecchymosis), discontinue the medication immediately and seek medical attention.
5. Precautions
Conduct regular monitoring of blood routine, hepatic and renal function, and electrocardiogram during the medication period.
Avoid combined use with anticoagulants or other antineoplastic drugs unless evaluated and approved by a doctor.
This drug is contraindicated in pregnant women, lactating women, and patients with severe hepatic or renal insufficiency.
6. Storage Conditions
Store in a dry place below 30℃ away from light. Keep the medicine out of the reach of children.