The usual dosage of fluzoparib capsules is 150 mg (1 capsule) twice daily, which may be taken on an empty stomach or with meals. The specific dosage shall be adjusted based on the patient's condition, tolerability and the physician’s guidance. This drug is a prescription medicine and must be evaluated by a professional physician before use. During treatment, patients shall strictly follow the doctor’s advice and shall not adjust the dosage or discontinue the drug without authorization.
Dosage Instructions
1. Standard Dosage
The recommended initial dosage is 150 mg twice daily, with an interval of approximately 12 hours between doses.
Swallow the capsule whole; do not chew or dissolve it. The drug may be taken on an empty stomach or with meals, and the same dosing time should be maintained daily.
2. Dosage Adjustment
In case of severe adverse reactions (e.g., hematological toxicity, gastrointestinal reactions), the physician may suspend the medication or reduce the dosage to 100 mg twice daily, or even 50 mg twice daily.
Caution is advised for patients with hepatic or renal impairment, and the dosage must be adjusted according to liver function (Child-Pugh classification) or renal function (creatinine clearance rate).
3. Treatment Course and Discontinuation
Treatment is generally continued until disease progression or the occurrence of intolerable toxic reactions.
The decision to discontinue the drug or adjust the treatment regimen shall be made by the physician based on the patient’s specific condition.
Precautions
Follow the physician’s advice for medication: Fluzoparib is only available with a physician’s prescription. During treatment, patients shall conduct regular rechecks of blood routine, liver and kidney function and other related indicators.
Adverse reaction monitoring
Common adverse reactions include anemia, nausea, fatigue, etc. Immediate medical attention is required if severe reactions occur.
Drug-drug interactions
Avoid concomitant use with potent CYP3A inhibitors or inducers. Patients shall inform the physician of any other medications they are taking.
Management of Special Situations
Missed Dose
If the missed dose is within 6 hours of the regular dosing interval, the missed dose may be taken as a supplement; if more than 6 hours have passed, skip the missed dose and take the next dose as originally scheduled.
Overdose
In case of accidental overdose, seek immediate medical attention and receive symptomatic and supportive treatment.
Disclaimer: This content is for popular science reference only. The specific medication plan shall be subject to the advice of the attending physician. If any abnormal symptoms occur during treatment, please contact a medical institution in a timely manner.
