The standard dosage of zanubrutinib is oral administration twice daily, 160 mg per dose (equivalent to 2 capsules of 80 mg strength), once in the morning and once in the evening, totaling 4 capsules per day. The specific dosage must be strictly followed as prescribed by a physician, and may be adjusted according to the patient’s disease type, physical condition, treatment response and adverse reactions. Do not increase, decrease the dosage or discontinue the medication without medical advice.
Precautions
1. Administration Guidelines
Take the medication at a fixed time every day. Swallow the capsules whole; do not break, open or chew them.
If a dose is missed and the delay is within 3 hours of the scheduled time, take the missed dose immediately. If more than 3 hours have passed, skip the missed dose and resume the regular dosing schedule for the next dose.
Avoid concomitant consumption with grapefruit, pomelo or other foods that may interfere with drug metabolism.
2. Dosage Adjustment
The physician may adjust the dosage or temporarily suspend treatment in cases of impaired hepatic or renal function, or occurrence of severe adverse reactions (e.g., infection, bleeding, cytopenia).
Regular monitoring of complete blood count, hepatic and renal function, and infection markers is required during treatment.
3. Adverse Reaction Management
Common adverse reactions include diarrhea, rash, fatigue, etc. Seek immediate medical attention for severe adverse events such as cardiac arrhythmia and serious infection.
Contact a healthcare provider promptly if unusual bruising, fever or dyspnea occurs after taking the medication.
Medical Guidance
Zanubrutinib is a prescription medication and should only be used following evaluation by a qualified physician. Regular follow-up visits are required during treatment, and the physician will optimize the regimen based on treatment efficacy and tolerability. Patients must not adjust the medication regimen on their own, as this may compromise treatment efficacy or increase health risks.
