Its a targeted drug with precise efficacy, convenient administration, controllable safety profile, and prominent advantages in addressing specific disease indications.
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Privacy On January 16, 2025, Limertinib Tablets were approved for marketing by the National Medical Products Administration (NMPA).
It can effectively meet the treatment needs of patients with relevant indications and provide a high-quality therapeutic regimen with both tolerability and efficacy for specific populations in clinical practice.
This product is indicated for:
1.First-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 (L858R) substitution mutation.
2.Treatment of adult patients with locally advanced or metastatic NSCLC who have experienced disease progression during or after prior treatment with EGFR tyrosine kinase inhibitors (TKIs) and are confirmed to be positive for EGFR T790M mutation by detection.
The recommended dose of this product is 80 mg each time, twice daily. It can be taken on an empty stomach or after meals, with an interval of 12 hours between the two doses. Treatment should be continued until disease progression or intolerable adverse reactions occur.
The recommended dose of this product is 160 mg each time, twice daily. It should be taken on an empty stomach (1 hour before meals or 2 hours after meals), with an interval of 12 hours between the two doses. Treatment should be continued until disease progression or intolerable adverse reactions occur.
It is recommended to take the medicine at approximately the same time each day. Swallow the tablet whole with an appropriate amount of warm water; do not chew or crush it. If a dose is missed, take the missed dose if the interval from the next scheduled dose is more than 6 hours.
Contraindicated in patients with hypersensitivity to any component of this product.
Common adverse reactions of Limertinib include gastrointestinal system disorders (diarrhea, nausea, vomiting, oral mucositis, xerostomia, and oral ulcer), skin and subcutaneous tissue disorders (rash, pruritus, and acneiform dermatitis), anemia, metabolic and nutritional disorders (hypokalemia, hypertriglyceridemia, hyperuricemia, decreased appetite, hypoalbuminemia, hypercholesterolemia, hypocalcemia, hypophosphatemia, and hyperglycemia), urinary tract infection, renal and urinary system disorders (proteinuria and hematuria), asthenia, dizziness, and cardiac disorders (supraventricular extrasystoles and first-degree atrioventricular block).
Severe adverse reactions occurred in 5.4% (9 cases) of patients, and the severe adverse reaction with an incidence ≥ 1% was interstitial lung disease.
For more detailed drug information, please consult the official package leaflet.
Liertinib Tablets (trade name: Aoyixin) is an ···...【详情】
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Liotinib is a tyrosine kinase inhibitor (TKI) primarily indicated for the treatment of malignant tumors driven by specific gene mutations, such as non-small cell lung cancer (NSCLC) and thyroid cancer.
Dear Customers,Liotinib is a prescription-targeted anticancer drug. Orders must be placed with a valid prescription. We will strictly comply with pharmaceutical regulatory requirements and arrange mail delivery services for all eligible orders.
The price of Liotinib typically ranges from approximately $300 to $800 per box. The exact cost varies significantly depending on factors including drug specifications, geographic region, and purchase channels.
Liotinib is a targeted therapeutic agent that exerts its anticancer effects primarily by inhibiting specific abnormal proteins or signaling pathways within tumor cells, thereby achieving precise cancer treatment outcomes. Unlike traditional chemotherapeutic drugs, targeted agents can act more selectively on tumor-associated molecular targets, minimizing damage to normal cells.
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