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Limertinib
Limertinib

Limertinib(利厄替尼片)

Its a targeted drug with precise efficacy, convenient administration, controllable safety profile, and prominent advantages in addressing specific disease indications.

  • 80mg*20tablets

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Introduction of Limertinib

On January 16, 2025, Limertinib Tablets were approved for marketing by the National Medical Products Administration (NMPA). 

It can effectively meet the treatment needs of patients with relevant indications and provide a high-quality therapeutic regimen with both tolerability and efficacy for specific populations in clinical practice.

Indications

This product is indicated for:

1.First-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 (L858R) substitution mutation.

2.Treatment of adult patients with locally advanced or metastatic NSCLC who have experienced disease progression during or after prior treatment with EGFR tyrosine kinase inhibitors (TKIs) and are confirmed to be positive for EGFR T790M mutation by detection.


Overview

Generic Name
Limertinib Tablets,利厄替尼片
Brand Name
奥壹新
Drug Type
Rx Drug,targeted drug
Approval No.
国药准字H20250004
Active Ingredient
Limertinib
Dosage Form
80mg*20tablets
Specification
Tablet
Description
Limertinib Tablets are pink film-coated tablets, which appear white after removing the coating.
Expiry Date
36 months
Manufacturer
Jiangsu Aosaikang Pharmaceutical Co., Ltd.
Storage
Store at a temperature not exceeding 30℃. Keep this product out of the reach of children.

Dosage and Administration

First-line treatment of NSCLC

The recommended dose of this product is 80 mg each time, twice daily. It can be taken on an empty stomach or after meals, with an interval of 12 hours between the two doses. Treatment should be continued until disease progression or intolerable adverse reactions occur.

Second-line treatment of NSCLC

The recommended dose of this product is 160 mg each time, twice daily. It should be taken on an empty stomach (1 hour before meals or 2 hours after meals), with an interval of 12 hours between the two doses. Treatment should be continued until disease progression or intolerable adverse reactions occur.

It is recommended to take the medicine at approximately the same time each day. Swallow the tablet whole with an appropriate amount of warm water; do not chew or crush it. If a dose is missed, take the missed dose if the interval from the next scheduled dose is more than 6 hours.

Contraindications

Contraindicated in patients with hypersensitivity to any component of this product.

Adverse Reactions

Common adverse reactions of Limertinib include gastrointestinal system disorders (diarrhea, nausea, vomiting, oral mucositis, xerostomia, and oral ulcer), skin and subcutaneous tissue disorders (rash, pruritus, and acneiform dermatitis), anemia, metabolic and nutritional disorders (hypokalemia, hypertriglyceridemia, hyperuricemia, decreased appetite, hypoalbuminemia, hypercholesterolemia, hypocalcemia, hypophosphatemia, and hyperglycemia), urinary tract infection, renal and urinary system disorders (proteinuria and hematuria), asthenia, dizziness, and cardiac disorders (supraventricular extrasystoles and first-degree atrioventricular block).

Severe adverse reactions occurred in 5.4% (9 cases) of patients, and the severe adverse reaction with an incidence ≥ 1% was interstitial lung disease.

For more detailed drug information, please consult the official package leaflet.

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Contact Information

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Pharmacy Purchase Notes

What Kind of Drug is Liotinib? +

Liotinib is a tyrosine kinase inhibitor (TKI) primarily indicated for the treatment of malignant tumors driven by specific gene mutations, such as non-small cell lung cancer (NSCLC) and thyroid cancer.

Can Liotinib Be Delivered by Mail? +

Dear Customers,Liotinib is a prescription-targeted anticancer drug. Orders must be placed with a valid prescription. We will strictly comply with pharmaceutical regulatory requirements and arrange mail delivery services for all eligible orders.

How Much Does One Box of Liotinib Cost? +

The price of Liotinib typically ranges from approximately $300 to $800 per box. The exact cost varies significantly depending on factors including drug specifications, geographic region, and purchase channels.

Is Liotinib a Targeted Drug? +

Liotinib is a targeted therapeutic agent that exerts its anticancer effects primarily by inhibiting specific abnormal proteins or signaling pathways within tumor cells, thereby achieving precise cancer treatment outcomes. Unlike traditional chemotherapeutic drugs, targeted agents can act more selectively on tumor-associated molecular targets, minimizing damage to normal cells.

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